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Systematic Reviews : The Systematic Review Process

Systematic Review and Meta-Analysis Process

The figure1 below gives a high-level overview of the stages of the meta-analysis process. Other evidence synthesis methods may omit steps in the meta-analysis process; for example, systematic reviews will not include Step 14 'meta-analyze'.

image of meta-analysis process

 

1Tsafnet, G., Glasziou, P., Choong, M.K., et al. Systematic review automation technologies. Systematic Reviews 2014; 3:74;  http://www.systematicreviewsjournal.com/content/3/1/74.

Parts of a Systematic Review

Your systematic review should contain each of the following sections:
 

  1. TITLE - The title should identify what the report is about and what it is (systematic review, meta-analysis, or both).
     
  2. ABSTRACT - The abstract should provide a structured summary of the parts of the review.
     
  3. INTRODUCTION - The introduction should describe why the review is needed (the rationale for the review) and the review objectives (the question being addressed).
     
  4. METHODS - The methods section should include a thorough description of how the systematic review was conducted, including whether or not you created a protocol and where it is registered, what your eligibility or inclusion criteria were, what your sources of information were and the date they were searched, your full search strategy, your process for selecting studies and collecting data, the data collected, how risk of bias was assessed on an individual study basis and across studies, your summary measures (risk ratio, difference in mean, etc.), and how results were synthesized and analyzed. If you have a protocol, much of this information can be taken from there.
     
  5. RESULTS - The results section should include the findings of your review, including a description of the studies screened for eligibility and the studies selected, the characteristics of the included studies, the risk of bias for each individual study, the results of each individual study, a synthesis of the data for each outcome considered, the risk of bias across studies, and any additional analysis conducted.
     
  6. DISCUSSION - The discussion section should include a summary of the main findings of the report, including the strength of evidence for each outcome and the findings' relevance to key groups, the limitations of the report, and a conclusion that contains a general interpretation of the results.
     
  7. FUNDING - Any funding received for the review and the role of the funders in the review should be described in this section.
     

For more information, check out the PRISMA checklist.

Role of the Librarian

According to the Institute of Medicine Standards for Systematic Reviews, the systematic review team should work with a librarian during the following steps:

3.1.1     Work with a librarian or other information specialist trained in performing systematic reviews to plan the search strategy
3.1.2 Design the search strategy to address each key research question
3.1.3 Use an independent librarian or other information specialist to peer review the search strategy


In addition to the standards outlined by the Institute of Medicine, a trained librarian can help with numerous steps throughout the planning, conducting, and reporting phases of your systematic review. With our specialized knowledge of the systematic review process, we can save you time and confusion by providing guidance on the systematic review process and the best practices for many of the steps along the way, as well as actively helping to develop and refine your topic, create systematic literature searches of all relevant databases, search the grey literature, and provide information for your PRISMA figure and Methods section.

Image from the University of North Carolina's Systematic Reviews guide